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Chronic Lymphocytic Leukemia


Chronic Lymphocytic Luekemia: Leukemia is a group of diseases in which the body’s bone marrow makes too many of an abnormal type of white blood cell. Chronic lymphocytic leukemia (Cll Leukemia) is a cancer of the lymphocyte, a disorder of morphologically mature, are unable to perform their proper functions and the most common adult leukemia in the Western world. It’s typically and indolent disease of older individuals. 95% of chronic lymphocytic leukemia is B-cell origin and the remainder is T-cell leukemia. Leukemia and lymphoma occur at any age but are most frequent in adult, most leukemia in childhood are all leukemia (acute lymphoblastic leukemia)

Signs and symptoms diagnosis before treatment of Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia is the most slowly progressive form of leukemia; in the early stages of cll leukemia (chronic lymphocytic leukemia) many patients have no symptoms at the time of diagnosis. When chronic lymphocytic leukemia begins to replace normal bone marrow, low blood counts can cause infections, anemia and bleeding. Common chronic lymphocytic leukemia symptoms are feeling tired, fever and infection, painless swelling of the lymph nodes in the underarm, neck, groin and stomach. There is a formal staging system of chronic lymphocytic leukemia: RAI stage 0 to I (lymphocyte count (0) and lymph nodes (I)), RAI stage II: intermediate stage of the disease, the spleen becomes enlarged, RAI stage III to stage IV: final stage of the disease, bone marrow function is disturbed and significant decreasing in red blood cell. There are many risk factors for leukemia in childhood including genetics, exposure to radiation, various genetic diseass and Down syndrome and exposure to various drugs.

Chronic Lymphocytic Leukemia: Certain factors affect treatment options and prognosis

Treatment options depend on:
1) Red blood cell, platelet blood counts and white blood cell.
2) The response to initial treatment and whether there are symptoms: weight loss, chills and fever
3) The stage of disease and whether the spleen, liver are enlarged and whether the chronic lymphocytic leukemia has recurred
Cll leukemia prognosis depends on
1) The stage of disease and whether the chronic lymphocytic leukemia gets better with treatment and the chronic lymphocytic leukemia progress to lymphoma
2) Whether lymphocytes are spread throughout the bone marrow and there is a change in the DNA
3) The patient’s general health.
Chronic lymphocytic leukemia Chemotherapy and Drug Therapy
Way to Help Patients: You could be given drugs as pills to swallow by through a catheter or injection. During chemotherapy, you will be given potent drugs that must be toxic enough to kill leukemic cells but normal cell can get side effects. Patients commonly will be treated by combine drugs and chemotherapy to treat chronic lymphocytic leukemia (CLL).

Chronic Lymphocytic Leukemia Stem cell transplantation

Stem cell (allogeneic bone marrow) is rarely used as first line treatment for chronic lymphocytic leukemia due to its risk. Autologous stem cell transplantation, a lower risk treatment using the patient’s own blood cells, isn’t curative. CLL may transform into Richter’s syndrome: the development of fast growing diffuse large B cell lymphoma, Hodgkin’s lymphoma, prolymphocytic leukemia in a patient who has CLL.

Latest News and Chronic Lymphocytic Leukemia Related Articles

Acute Lymphoblastic Leukemia: Acute lymphoblastic leukemia, treatment acute lymphoblastic leukemia and all leukemia information

Leukemia Symptoms in Adults are loss of appetite, tiny red spots under the skin (petechiae), low grade fever, weight loss, joint pain, easy bruising caused by low level of platelets in blood.

Symptoms of Leukemia in Women: First occurring signs in the development of acute forms of leukemia are bruising and bleedings, weakness, chills, recurrent infections or lassitude

Cll Leukemia Life Expectancy:The new study have found that approximately 50 percent of CLL (Chronic lymphocytic leukemia) patients who are diagnosed in the early stage of the disease live for more than 12 years.